Structural insights into the role of reduced cysteine residues in SOD1 amyloid filament formation

Proceedings of the National Academy of Sciences, Volume 122, Issue 5, February 2025. SignificanceAlthough Cu/Zn superoxide dismutase (SOD1) primarily detoxifies cells by scavengingsuperoxide radical (O2•-), it also contributes to amyotrophic lateral sclerosis (ALS) by generating unusual amyloid filaments. We found that mutant SOD1 …

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‘Back to plastic’: Trump signs order for plastic straws as he declares paper ones ‘don’t work’

President Donald Trump says he is banning federal use of paper straws, saying they “don’t work” and don’t last very long. Instead he wants the government to exclusively move to plastic. Trump signed an executive order to reverse federal policies that encourage paper straws and restrict plastic straws…

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