Structural insights into the role of reduced cysteine residues in SOD1 amyloid filament formation

Proceedings of the National Academy of Sciences, Volume 122, Issue 5, February 2025. SignificanceAlthough Cu/Zn superoxide dismutase (SOD1) primarily detoxifies cells by scavengingsuperoxide radical (O2•-), it also contributes to amyotrophic lateral sclerosis (ALS) by generating unusual amyloid filaments. We found that mutant SOD1 …

Read more

‘Back to plastic’: Trump signs order for plastic straws as he declares paper ones ‘don’t work’

President Donald Trump says he is banning federal use of paper straws, saying they “don’t work” and don’t last very long. Instead he wants the government to exclusively move to plastic. Trump signed an executive order to reverse federal policies that encourage paper straws and restrict plastic straws…

Read more

Analysis finds flaw in ‘Protura-sister’ hypothesis: Reassessing early hexapod phylogeny

The early lineages of hexapods (broadly defined insects) have long been debated. Researchers at University of Tsukuba and collaborators critically examined the newly proposed “Protura-sister” phylogenetic hypothesis. This analysis revealed a fundamental flaw in the hypothesis, reinforcing the validity of the previously established “Ellipura” hypothesis…

Read more

How a student’s teenage curiosity led to the first megalodon discovery in Canada

Louis-Philippe Bateman’s fascination with megalodon began with a single sentence in a book about Canada’s geological evolution. It described giant, mysterious fossilized shark teeth discovered in the 1960s by fishermen dredging for scallops off Canada’s Atlantic coast. The curiosity felt by the teenager with a budding interest in paleontology would resurface in a meaningful way

Read more

This website is using cookies to improve the user-friendliness. You agree by using the website further.

Privacy policy
Skip to content