De novo design of D-peptide ligands: Application to influenza virus hemagglutinin

Proceedings of the National Academy of Sciences, Volume 122, Issue 26, July 2025. SignificanceAlthough D-peptides offer superior metabolic stability and immunogenicity properties compared to L-peptides, their discovery has been limited by current screening methods. We introduce a computational strategy for the de novo design of D…

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NASA Welcomes Axiom Mission 4 to the International Space Station

A SpaceX Dragon spacecraft carrying the Axiom Mission 4 crew docks to the space-facing port of the International Space Station’s Harmony module on June 26. Axiom Mission 4 is the fourth all-private astronaut mission to the orbiting laboratory, welcoming commander Peggy Whitson, former NASA astronaut and director of human spaceflight at Axiom Space…

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10 Times Real Laws Were Based on Bizarre Hypotheticals

Laws are supposed to be grounded in logic, necessity, and public safety—but sometimes, they sound more like punchlines than policies. Across the world, and especially in the U.S., lawmakers have occasionally passed statutes so strangely specific that they seem invented for a comedy sketch. From regulating the speed of UFOs to outlawing moose-pushing from airplanes…

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